Methods

Pozo C, Guillén-Gosálbez G, Sorribas A, Jimenez L. (2012) Identifying the preferred subset of enzymatic profiles in nonlinear kinetic metabolic models via multi-objective global optimization and Pareto filters. PLoS ONE 7(9): e43487. doi:10.1371/journal.pone.0043487

Guillén-Gosálbez G, Miró A, Alves R, Sorribas A, Jimenez L. (2013) Identification of regulatory structure and kinetic parameters of biochemical networks via mixed-integer dynamic optimization. BMC Systems Biology 7(1):113

Pozo C, Guillén-Gosálbez G, Sorribas A, Jimenez L (2011) A spatial branch-and-bound framework for the global optimization of kinetic models of metabolic networks.Source: Industrial & Engineering Chemistry Research 50: 5225-5238 DOI: 10.1021/ie101368k

Karathia HM, Vilaprinyo E, Sorribas A, Alves R. S. cerevisiae as a model organism: Strengths & drawbacks (2011) PLoS One 6(2):e16015

Vegetal biotechnology

Farré G, Maiam Rivera S, Alves R, Vilaprinyo E, Sorribas A, Canela R, Naqvi S, Sandmann G, Capell T, Zhu C, Christou P (2013) Targeted transcriptomic and metabolic profiling reveals temporal bottlenecks in the maize carotenoid pathway that may be addressed by multigene engineering. The Plant Journal doi: 10.1111/tpj.12214

Bai, C; Maiam R, Sol; Medina, V; Alves, R; Vilaprinyo, E; Sorribas, A; Canela, R; Capell, T; Sandmann, G; Christou, P; Zhu, C. (2014) An in vitro system for the rapid functional characterization of genes involved in carotenoid biosynthesis and accumulation. The Plant Journal (2014) doi: 10.1111/tpj.12384

Comas J, Benfeitas R, Vilaprinyo E, Sorribas A, Solsona F, Farré G, Berman J, Zorrilla U, Capell T, Sandmann G, Zhu C, Christou P, Alves R. (2016) Identification of line-specific strategies for improving carotenoid production in synthetic maize through data-driven mathematical modeling. Plant J. 2016 Sep;87(5):455-71. doi: 10.1111/tpj.13210. Epub 2016 Jul 18.